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Antigenic Specificity | EPO Receptor Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.Protein Function: R |
Immunogen | Immunogen: E Coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225). Subcellular Localization: Isoform EPOR-F: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells. |
Other Names | [Erythropoietin receptor; EPO-R; Epor] |
Gene, Accession # | [Epor], Gene ID: 13857, NCBI: NP_034279.3, UniProt: P14753 |
Catalog # | MBS1750400 |
Price | $280 |
Order / More Info | EPO Receptor Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |