BACE (S498), 476-501 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BACE (S498), 476-501 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine, rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This BACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-501 amino acids from human BACE. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. |
| Immunogen | n/a |
| Other Names | [Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; BACE; KIAA1149] |
| Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817 |
| Catalog # | MBS9205538 |
| Price | $165, $370 |
| Order / More Info | BACE (S498), 476-501 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Xie, J., et al., J. Biol. Chem. 280(14):13824-13832 (2005). He, X., et al., J. Biol. Chem. 280(12):11696-11703 (2005). Huang, X.P., et al., J. Biol. Chem. 279(36):37886-37894 (2004). Chiocco, M.J., et al., J. Biol. Chem. 279(50):52535-52542 (2004). Yang, H.C., et al., J. Neurochem. 91(6):1249-1259 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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