KRT8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKRT8
Clone[AT3D11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG3, k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionKeratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been f
ImmunogenImmunogen: Recombinant human KRT8 (1-483aa) purified from E. coli
Other Names[Keratin type II cytoskeletal 8; Keratin; type II cytoskeletal 8; keratin 8; CARD2; CK-8; CK8; CYK8; K2C8; K8; KO], [KRT8; KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; CYK8; CK-8; K8]
Gene, Accession #[KRT8], Gene ID: 3856, NCBI: NP_002264, UniProt: P05787
Catalog #MBS200222
Price$240, $315
Order / More InfoKRT8 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMoriya, T., et al. (2006) Med Mol Morphol 39 (1): 8-13; Leitner, A., et al. (2012) Biophys J 18;103 (2): 195-201
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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