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Antigenic Specificity | Mouse Actl6a (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Actl6a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 295-320 amino acids from the C-terminal region of Mouse Actl6a. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote i |
Immunogen | n/a |
Other Names | [Actin-like protein 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; BRG1-associated factor 53A; BAF53A; Actl6a; Actl6; Baf53a] |
Gene, Accession # | [Actl6a], Gene ID: 56456, NCBI: NP_062647.2, UniProt: Q9Z2N8 |
Catalog # | MBS9206805 |
Price | $165, $370 |
Order / More Info | Mouse Actl6a (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhao K.,et al.Cell 95:625-636(1998). Carninci P.,et al.Science 309:1559-1563(2005). Lessard J.,et al.Neuron 55:201-215(2007). |