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Antigenic Specificity | Arrestin-beta-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Arrestin-beta-1 Polyclonal Antibody detects endogenous levels of Arrestin-beta-1 protein. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. A |
Immunogen | Immunogen: Synthesized peptide derived from human Arrestin-beta-1 around the non-phosphorylation site of S412 |
Other Names | [Rabbit Arrestin-beta-1; ARR1; Beta-arrestin-1; Arrestin beta-1] |
Gene, Accession # | [ARRB1], Gene ID: 408, NCBI: NP_004032.2, UniProt: P49407 |
Catalog # | MBS9701443 |
Price | $130, $220, $325 |
Order / More Info | Arrestin-beta-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |