Edit |   |
---|---|
Antigenic Specificity | CEBPB |
Clone | [3H9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen. |
Immunogen | Immunogen: Purified recombinant fragment of human CEBPB expressed in E. Coli. |
Other Names | [LAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080; C/EBP-beta] |
Gene, Accession # | [CEBPB], Gene ID: 1051, NCBI: NP_005185.2, UniProt: P17676 |
Catalog # | MBS8538817 |
Price | $280 |
Order / More Info | CEBPB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |