KCNE1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KCNE1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: KCNE1 antibody detects endogenous levels of total KCNE1. Description: Voltage-gated potassium channels play a variety of important roles in human health and disease (1, 2). KCNE1, also known as MinK, belongs to a family of small transmembrane proteins (KCNE1, 2, 3, 4, and KCNE1L) that modulate the activity of several voltage-gated K+ channels (3-5). KCNE1 functions as the modulatory beta-subunit of the pore-forming alpha-subunit KCNQ1, and alters several biophysical properties of KCNQ1 channels (6, 7). Research studies have shown that several inherited mutations in KCNE1 result in long QT syndrome (8-10) and deafness (11).Function: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel com |
| Immunogen | Immunogen: A synthesized peptide derived from human KCNE1 Subcellular Location: Membrane. Tissue Specificity: Expressed in lung, kidney, testis, ovaries, small intestine, peripheral blood leukocytes. Expressed in the heart (PubMed:19219384). Not detected in pancreas, spleen, prostate and colon. Restrictively localized in the apical membrane portion of epithelial cells. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep Similarity: Pig (92%), Bovine (82%), Horse (91%), Sheep (82%) |
| Other Names | [Delayed rectifier potassium channel subunit IsK; Human cardiac delayed rectifier potassium channel protein; IKs producing slow voltage gated potassium channel subunit beta Mink; IKs producing slow voltage-gated potassium channel subunit beta Mink; ISK; JLNS 2; JLNS; JLNS2; KCNE 1; KCNE1; KCNE1_HUMAN; LQT 5; LQT5; MGC33114; Minimal potassium channel; MinK; Potassium voltage gated channel Isk related family member 1; Potassium voltage gated channel Isk related subfamily member 1; Potassium voltage gated channel subfamily E member 1; Potassium voltage-gated channel subfamily E member 1] |
| Gene, Accession # | [KCNE1], Gene ID: 3753, NCBI: NP_000210.2, UniProt: P15382 |
| Catalog # | MBS9606969 |
| Price | $240, $280 |
| Order / More Info | KCNE1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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