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Antigenic Specificity | CAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This CAD gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.Protein Function: This protein is a fusion protein encoding four enzymatic activities |
Immunogen | Immunogen: E Coli-derived human CAD recombinant protein (Position: L1555-K1780). Subcellular Localization: Cytoplasm. |
Other Names | [CAD protein; Glutamine-dependent carbamoyl-phosphate synthase] |
Gene, Accession # | [CAD], Gene ID: 790, NCBI: NP_001293008.1, UniProt: P27708 |
Catalog # | MBS1750410 |
Price | $280 |
Order / More Info | CAD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |