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Antigenic Specificity | Human DR3 |
Clone | [ANC2D12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1k |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1.0 mg/ml |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Information: Human DR3 (TRAMP, LARD) was designated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction. Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFN? production. Clone ANC2D12 binds specifically to recombinant DR3 in EIA, but does not inhibit DR3 binding to TL1A. |
Immunogen | Immunogen: Recombinant DR3 |
Other Names | [human DR3/Biotin], [TNFRSF25; TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; LARD] |
Gene, Accession # | [DR3], Gene ID: 8718, NCBI: AAQ88676.1 |
Catalog # | MBS666208 |
Price | $440 |
Order / More Info | Human DR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) A Kaptein, et al. (2000) FEBS Lett 485:135. (2) T Migone, et al. (2002) Immunity 16:479. (3) S Targin, et al. (2004) 172: 7002. |