Human Beta-3 integrin subunit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Beta-3 integrin subunit |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | reactivity: human. cross reactivity: bovine |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, FS, Immunoassay (IA), Immunoprecipitation (IP), P, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody BV4 recognizes human beta3 integrin subunit present in Platelet glycoprotein GPIIb-IIIa (integrin alphaIIb/beta3, CD41/CD61) and in the vitronectin receptor (integrin alphaV/beta3, CD51/CD61). Intergins are a family of heterodimeric membrane glycoproteins expressed on diverse cell types which function as the major receptors for extracellular matrix and as cell-cell adhesion molecules. As adhesion molecules they play an important role in numerous biological processes such as platelet aggregation, inflammation, immune function, wound healing, tumour metastasis and tissue migration during embryogenesis. In addition integrins are involved in signaling pathways, transmitting signals both into an out f |
| Immunogen | n/a |
| Other Names | [Platelet membrane glycoprotein IIIa, GPIIIa], [Itgb3; Itgb3; CD61; GP3A; INGRB3; GPIIIa] |
| Gene, Accession # | Gene ID: 16416, NCBI: AAB94676.1 |
| Catalog # | MBS584087 |
| Price | $520 |
| Order / More Info | Human Beta-3 integrin subunit Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Soldi, R et al; Role of alpha v beta 3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J 1999, 18:882 2. Kimmins, S eta l: Immunohistochemical localization of integrin alpha v beta 3 and osteopontin suggests that they do not interact during embryo implantation in ruminants. Reprod Biol and Endocrinol. 2004, 2:19 3. Neto, D et al; Alpha-v-beta3 integrin expression in melanocytic nevi and cutaneous melanoma. J Cutan Pathol. 2007, 34: 851 4. Tang, N et al; N-terminal and C-terminal heparin-binding domain polypeptides derived from fibronectin reduce adhesion and invasion of liver cancer cells. BMC Cancer 2010, 10: 552 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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