SUV39H2 (C-term), 367-395 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SUV39H2 (C-term), 367-395 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey, mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SUV39H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-395 amino acids from the C-terminal region of human SUV39H2. Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to h |
| Immunogen | n/a |
| Other Names | [Histone-lysine N-methyltransferase SUV39H2; Histone H3-K9 methyltransferase 2; H3-K9-HMTase 2; Lysine N-methyltransferase 1B; Suppressor of variegation 3-9 homolog 2; Su(var)3-9 homolog 2; SUV39H2; KMT1B] |
| Gene, Accession # | [SUV39H2], Gene ID: 79723, NCBI: NP_001180353.1, UniProt: Q9H5I1 |
| Catalog # | MBS9213616 |
| Price | $165, $370 |
| Order / More Info | SUV39H2 (C-term), 367-395 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sun, X.J., et al. PLoS ONE 3 (1), E1499 (2008) : Wu, C., et al. Proteomics 7(11):1775-1785(2007) Yoon, K.A., et al. Carcinogenesis 27(11):2217-2222(2006) Frontelo, P., et al. Oncogene 23(30):5242-5251(2004) Deloukas, P., et al. Nature 429(6990):375-381(2004) |
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MYBIOSOURCE INC.
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