DR6 (Human) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DR6 (Human) |
| Clone | [Luke-1] |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human DR6. Apoptosis is induced by certain cytokines including TNF and Fas ligand (CD95L) of the TNF family through their death domain containing receptors, TNF-R1 and Fas (CD95). Several death receptors including DR3, TRAIL-R1, and TRAIL-R2 were identified. A death domain containing receptor in the TNF-R family was cloned and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappaB and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified yet. T cells from DR6-deficient mice showed preference toward Th2 differentiation in vitro, suggesting that DR6, working thr |
| Immunogen | Immunogen: Recombinant human DR6 (death receptor-6) (aa 42-335). |
| Other Names | [DR6], [TNFRSF21; TNFRSF21; DR6; CD358; BM-018; DR6] |
| Gene, Accession # | [Death receptor-6; TNFRSF 21], Gene ID: 27242, NCBI: O75509.1, UniProt: O75509 |
| Catalog # | MBS565147 |
| Price | $450 |
| Order / More Info | DR6 (Human) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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