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Antigenic Specificity | ITGA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.3mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ITGA4 protein. The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Fusion protein of human ITGA4 Immunogen Type: Protein |
Other Names | [IA4; CD49D] |
Gene, Accession # | [ITGA4], Gene ID: 3676, NCBI: NP_000876.3, UniProt: P13612 |
Catalog # | MBS9416929 |
Price | $255 |
Order / More Info | ITGA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |