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Antigenic Specificity | NOD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human NOD2 (NP 071445.1). |
Other Names | [Nucleotide-binding oligomerization domain-containing protein 2; Nucleotide-binding oligomerization domain-containing protein 2; nucleotide-binding oligomerization domain-containing protein 2; nucleotide binding oligomerization domain containing 2; Caspase recruitment domain-containing protein 15; Inflammatory bowel disease protein 1] |
Gene, Accession # | [NOD2], Gene ID: 64127, NCBI: Q9HC29.1, UniProt: Q9HC29 |
Catalog # | MBS8570672 |
Price | $280 |
Order / More Info | NOD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |