MAP3K7IP1, 416-445 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MAP3K7IP1, 416-445 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.33 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAP3K7IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-445 amino acids from human MAP3K7IP1. MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and a |
| Immunogen | n/a |
| Other Names | [TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1; TAB1; MAP3K7IP1] |
| Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q15750 |
| Catalog # | MBS9209282 |
| Price | $165, $370 |
| Order / More Info | MAP3K7IP1, 416-445 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Arch,R.H., et.al., Genes Dev. 12 (18), 2821-2830 (1998) Yamaguchi,K., et.al., EMBO J. 18 (1), 179-187 (1999) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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