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Antigenic Specificity | SAP102 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene. DLG3 is a member of the membrane-associated guanylate kinase (MAGUK) superfamily of proteins. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation.Protein Function: Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. |
Immunogen | Immunogen: E Coli-derived human SAP102 recombinant protein (Position: E749-L817). Human SAP102 shares 98.6% amino acid (aa) sequence identity with both mouse and rat SAP102. |
Other Names | [Disks large homolog 3; Neuroendocrine-DLG; Synapse-associated protein 102; SAP-102; SAP102; XLMR; DLG3; KIAA1232] |
Gene, Accession # | [SAP102], Gene ID: 1741, NCBI: NP_001159750.1, UniProt: Q92796 |
Catalog # | MBS1750864 |
Price | $315 |
Order / More Info | SAP102 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |