Edit |   |
Antigenic Specificity | CD9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for CD9 antigen (CD9) detection. Background: CD9 antigen is a protein that in humans is encoded by the CD9 gene. CD9 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. This protein also seems to be a key part in the egg-sperm fusion during mammalian fertilization. While oocytes are ovulated, CD9-deficient oocytes are not properly fused with sperm upon fertilization. CD9 is located in the microvillar membrane of th |
Immunogen | Immunogen: E Coli-derived mouse CD9 recombinant protein (Position: T110-I193). Mouse CD9 shares 77.4% and 86.9% amino acid (aa) sequence identity with human and rat CD9, respectively. |
Other Names | [Tetraspanin 29; Tetraspanin-29; 5H9; 5H9 antigen; BA2; BTCC 1; BTCC1; CD9; CD 9; CD9 antigen; CD9 antigen p24; CD9 molecule; DRAP 27; DRAP27; GIG2; MIC3; MRP 1; MRP-1; MRP1; p24; p24 antigen; Tspan 29; Tspan-29; TSPAN29; P40240; CD9 antigen; CD9 molecule], [Cd9; Cd9; Tspan29] |
Gene, Accession # | [CD9], Gene ID: 12527, NCBI: NP_031683.1, UniProt: P40240 |
Catalog # | MBS178430 |
Price | $315 |
Order / More Info | CD9 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Katz F, Povey S, Parkar M, Schneider C, Sutherland R, Stanley K, Solomon E, Greaves M (March 1984). Chromosome assignment of monoclonal antibody-defined determinants on human leukemic cells. Eur J Immunol 13(12): 1008-1013. 2. Le Naour F, Rubinstein E, Jasmin C, Prenant M, Boucheix C (2000). Severely Reduced Female Fertility in CD9-Deficient Mice. Science 287(5451): 319-321.3. Runge KE, Evans JE, He ZY, Gupta S, McDonald KL, Stahlberg H, Primakoff P, Myles DG (2007). Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution.Developmental Biology 304 (1): 317-325. |