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Antigenic Specificity | HSC70 |
Clone | [5C2-6G4-9A4] |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:27916661, PubMed:23018488). This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:279166 |
Immunogen | Immunogen: Purified recombinant protein expressed in E Coli. |
Other Names | [Heat shock cognate 71 KDa protein; HSC71; HSP73; HSPA8; HSPA8] |
Gene, Accession # | [HSC70], Gene ID: 3312, NCBI: NP_006588.1, UniProt: P11142 |
Catalog # | MBS8539883 |
Price | $280 |
Order / More Info | HSC70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |