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Antigenic Specificity | IL17RC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL17RC antibody detects endogenous levels of total IL17RC. Function: Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495).Subunit Structure: Heterodimer with IL17RA (PubMed:16785495, PubMed:18684971). Heterodimerization with IL17RA is independent of the cytoplasmic tail (By similarity). Ass |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane; Single-Pass Type I Membrane Protein. Note: Soluble isoforms may be produced. Tissue Specificity: Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) (PubMed:11706037). Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate (PubMed:11706037). Also detected in thyroid, trachea and adrenal gland (PubMed:17911633). Low expression in thymus and leukocyt |
Other Names | [IL 17 receptor C; IL 17RC; IL 17RL; IL17 receptor C; IL17F receptor; IL17RL; Interleukin 17 receptor C; Interleukin 17 receptor homolog; Interleukin 17 receptor like; Interleukin 17 receptor like protein] |
Gene, Accession # | [IL17RC], Gene ID: 84818, NCBI: NP_001190192.1, UniProt: Q8NAC3 |
Catalog # | MBS9606162 |
Price | $240, $280 |
Order / More Info | IL17RC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |