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Antigenic Specificity | p300 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: p300 Polyclonal Antibody detects endogenous levels of p300 protein. EP300 (E1A binding protein p300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human p300 |
Other Names | [Rabbit p300; EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300] |
Gene, Accession # | [p300], Gene ID: 2033, NCBI: NP_001420.2, UniProt: Q09472 |
Catalog # | MBS9707998 |
Price | $130, $220, $325 |
Order / More Info | p300 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |