MARCH8 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMARCH8 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against MARCH8. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARCH8
Other Names[E3 ubiquitin-protein ligase MARCH8 isoform a; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCH8; membrane associated ring-CH-type finger 8; Cellular modulator of immune recognition; c-MIR; Membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MARCH-VIII; RING finger protein 178]
Gene, Accession #[MARCH8], Gene ID: 220972, NCBI: NP_659458, UniProt: Q5T0T0
Catalog #MBS3206851
Price$335
Order / More InfoMARCH8 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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