Mouse LPAM-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse LPAM-1
Clone[2G18]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) - Paraffin, Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
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DescriptionThis antibody was selected for its ability to detect mouse CD45 positive leukocytes in IHC. The antibody is specific for a combinatorial determinate of integrin alpha4beta7complex. Integrin alpha4beta7 is composed of a 150 kD (alpha4 or CD49d) and a 130 kD (beta7) heterodimer, also known as CD49d/beta7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin alpha4beta7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with cell lysates of mouse lymphocytes. IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Other Names[mouse LPAM-1 (#2G18)], [Itgb7; Itgb7; Ly69]
Gene, Accession #[LPAM-1], Gene ID: 16421, NCBI: NP_038594.2, UniProt: P26011
Catalog #MBS690598
Price$490
Order / More InfoMouse LPAM-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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