CHRNB2 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHRNB2 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, human, mouse, porcine, rat
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against CHRNB2. It was validated on Western Blot and immunohistochemistryTarget Description: Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy. Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2
Other Names[neuronal acetylcholine receptor subunit beta-2; Neuronal acetylcholine receptor subunit beta-2; neuronal acetylcholine receptor subunit beta-2; cholinergic receptor nicotinic beta 2 subunit]
Gene, Accession #[CHRNB2], Gene ID: 1141, NCBI: NP_000739, UniProt: P17787
Catalog #MBS3202381
Price$290
Order / More InfoCHRNB2 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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