srrt (C-Term) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | srrt (C-Term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, zebrafish |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 733-766 amino acids from DANRE srrt. Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity). |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Serrate RNA effector molecule homolog; Arsenite-resistance protein 2; srrt; ars2] |
| Gene, Accession # | [srrt], Gene ID: 192311, NCBI: NP_775345.2, UniProt: Q66I22 |
| Catalog # | MBS9216846 |
| Price | $165, $370 |
| Order / More Info | srrt (C-Term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Golling G.,et al.Nat. Genet. 31:135-140(2002).Howe K.,et al.Nature 496:498-503(2013). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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