p62 (Human) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp62 (Human)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.025 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionRecognizes human p62. P62, also known as Sequestosome I, is a 62kDa, 440 amino acid protein, initially identified as a ligand of the SH2 domain of p56lck, now known to be expressed in many tissues. In addition to TRAF6, PEST and zinc finger motifs, p62 has a C-terminal ubiquitin binding association (UBA) domain with an affinity for multi-ubiquitin chains, and it is considered to serve as a scaffold protein, capable of binding to multiple signalling molecules and uniting receptor-mediated signalling events with ubiquitinylation. Elevated levels of p62 have been reported in breast tumours and in alcoholic liver disease where p62 has been shown to be involved in the formation of Mallory bodies. Several mutations in the p62 UBA domain have been
ImmunogenImmunogen: Synthetic peptide corresponding to aa 387-436 human p62.
Other Names[p62], [SQSTM1; SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B; FTDALS3; ORCA; OSIL; EBIAP; p60]
Gene, Accession #[SQSTM1; Sequestosome I], Gene ID: 8878, NCBI: Q13501.1, UniProt: Q13501
Catalog #MBS565334
Price$200, $460
Order / More Infop62 (Human) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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