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Antigenic Specificity | p62 (Human) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.025 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human p62. P62, also known as Sequestosome I, is a 62kDa, 440 amino acid protein, initially identified as a ligand of the SH2 domain of p56lck, now known to be expressed in many tissues. In addition to TRAF6, PEST and zinc finger motifs, p62 has a C-terminal ubiquitin binding association (UBA) domain with an affinity for multi-ubiquitin chains, and it is considered to serve as a scaffold protein, capable of binding to multiple signalling molecules and uniting receptor-mediated signalling events with ubiquitinylation. Elevated levels of p62 have been reported in breast tumours and in alcoholic liver disease where p62 has been shown to be involved in the formation of Mallory bodies. Several mutations in the p62 UBA domain have been |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 387-436 human p62. |
Other Names | [p62], [SQSTM1; SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B; FTDALS3; ORCA; OSIL; EBIAP; p60] |
Gene, Accession # | [SQSTM1; Sequestosome I], Gene ID: 8878, NCBI: Q13501.1, UniProt: Q13501 |
Catalog # | MBS565334 |
Price | $200, $460 |
Order / More Info | p62 (Human) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |