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Antigenic Specificity | Human DEDAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml. |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human DEDAF antibody recognizes human death effector domain associated factor (DEDAF), a 32kDa protein that associates with DED-containing proteins but does not itself contain a DED. DEDAF interacts with the death effector domains of FADD, DEDD and the proforms of caspase-8 and caspase-10. It augments the formation of complexes between CD95, FADD and caspase-8 at the cell membrane and enhances apoptosis. The protein was also independently identified as RING1 and YY1 binding protein (RYBP), which was implicated in the regulation of transcription. |
Immunogen | Immunogen: A peptide corresponding to amino acids 215-228 of human DEDAF. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human DEDAF was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [RING1 and YY1-binding protein; RING1 and YY1-binding protein; RING1 and YY1-binding protein; APAP-1; DED-associated factor; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1; apoptin-associating protein 1; death effector domain-associated factor; ring1 interactor RYBP; RING1 and YY1 binding protein; Apoptin-associating protein 1; APAP-1; Death effector domain-associated factor; DED-associated factor; YY1 and E4TF1-associated factor 1], [RYBP; RYBP; AAP1; DEDAF; YEAF1; DEDAF; YEAF1; APAP-1; DED-associated factor] |
Gene, Accession # | [DEDAF], Gene ID: 23429, NCBI: NP_036366.3, UniProt: Q8N488 |
Catalog # | MBS223345 |
Price | $405 |
Order / More Info | Human DEDAF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |