Edit |   |
---|---|
Antigenic Specificity | RBBP8 (C-term), 763-792 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 amino acids from the C-terminal region of human RBBP8. The protein encoded by this gene is a ubiquitouslyexpressed nuclear protein. It is found among several proteins thatbind directly to retinoblastoma protein, which regulates cellproliferation. This protein complexes with transcriptionalco-repressor CTBP. It is also associated with BRCA1 and is thoughtto modulate the functions of BRCA1 in transcriptional regulation,DNA repair, and/or cell cycle checkpoint control. It is suggestedthat this gene may itself be a tumor suppressor acting in the samepathway as BRCA1. Three transcript variants encoding t |
Immunogen | n/a |
Other Names | [DNA endonuclease RBBP8; 31--; CtBP-interacting protein; CtIP; Retinoblastoma-binding protein 8; RBBP-8; Retinoblastoma-interacting protein and myosin-like; RIM; Sporulation in the absence of SPO11 protein 2 homolog; SAE2; RBBP8; CTIP] |
Gene, Accession # | [RBBP8], Gene ID: 5932, NCBI: NP_002885.1, UniProt: Q99708 |
Catalog # | MBS9208784 |
Price | $165, $370 |
Order / More Info | RBBP8 (C-term), 763-792 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kaidi, A., et al. Science 329(5997):1348-1353(2010) Thye, T., et al. Nat. Genet. 42(9):739-741(2010) Notaridou, M., et al. Int. J. Cancer (2010) In press : Yasuno, K., et al. Nat. Genet. 42(5):420-425(2010) Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) : |