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Antigenic Specificity | OPA1 (form S1) (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat (predicted reactivity: chicken, zebrafish) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This OPA1(form S1) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1(form S1). Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. |
Immunogen | n/a |
Other Names | [Dynamin-like 120 kDa protein; mitochondrial; Optic atrophy protein 1; Dynamin-like 120 kDa protein; form S1; OPA1; KIAA0567] |
Gene, Accession # | [OPA1], Gene ID: 4976, NCBI: NP_056375.2, UniProt: O60313 |
Catalog # | MBS9201693 |
Price | $165, $370 |
Order / More Info | OPA1 (form S1) (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Nagase T.,et al.DNA Res. 5:31-39(1998). Wang W.,et al.Nucleic Acids Res. 39:44-58(2011). Muzny D.M.,et al.Nature 440:1194-1198(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Delettre C.,et al.Hum. Genet. 109:584-591(2001). |