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Antigenic Specificity | SDHB Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: SDHB(Succinate Dehydrogenase Complex, Subunit B, iron sulfur protein), also known as iron-sulfur subunit of complex II (Ip) or SDH2, HOMOLOG OF, is a protein that in humans is encoded by the SDHB gene. SDHB is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. The SDHB gene is mapped on 1p36.13. It is stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors, and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas, respectively. In affected |
Immunogen | Immunogen: E Coli-derived human SDHB recombinant protein (Position: A29-V280). Subcellular Localization: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Other Names | [Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial; Iron-sulfur subunit of complex II; Ip; SDHB; SDH; SDH1] |
Gene, Accession # | [SDHB], Gene ID: 6390, NCBI: NP_002991.2, UniProt: P21912 |
Catalog # | MBS1750563 |
Price | $315 |
Order / More Info | SDHB Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |