Phospho-p27Kip1 (T157) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-p27Kip1 (T157) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Dot Blot (DB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T157 of human p27Kip1. p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. |
| Immunogen | n/a |
| Other Names | [Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1; CDKN1B; KIP1] |
| Gene, Accession # | [CDKN1B], Gene ID: 1027, NCBI: NP_004055.1, UniProt: P46527 |
| Catalog # | MBS9214812 |
| Price | $165, $370 |
| Order / More Info | Phospho-p27Kip1 (T157) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kawamata, N., et al., Eur. J. Haematol. 74(5):424-429 (2005). Andreu, E.J., et al., Cancer Res. 65(8):3264-3272 (2005). Wingate, H., et al., J. Biol. Chem. 280(15):15148-15157 (2005). Wang, C., et al., J. Biol. Chem. 280(13):12339-12343 (2005). Rassidakis, G.Z., et al., Blood 105(2):827-829 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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