FZD1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FZD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: FZD1 antibody detects endogenous levels of total FZD1. Function: Receptor for Wnt proteins (PubMed:10557084). Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B (PubMed:10557084). Contradictory results showing activation by WNT7B have been described for mouse (By similarity). Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10557084). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10557084). A second signaling pathway involving PKC and calcium fluxes has been seen for some family m |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Membrane. Cell Membrane. Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Predicted Cross Reactivity: Pig, Zebrafish, Bovine Similarity: Pig (83%), Zebrafish (80%), Bovine (83%) |
| Other Names | [Chfz-1; Dfrizzled-1; DKFZp564G072; FLJ95923; Frizzled 1; Frizzled homolog 1 (Drosophila); Frizzled homolog 1; Frizzled-1; Fz receptor 1; Fz-1; Fz1; FZD1; FZD1_HUMAN; FzE1; hFz1; Rfz1; Wnt receptor; Xfrizzled-1] |
| Gene, Accession # | [FZD1], Gene ID: 8321, NCBI: NP_003496.1, UniProt: Q9UP38 |
| Catalog # | MBS9606334 |
| Price | $240, $280 |
| Order / More Info | FZD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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