MAP3K4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP3K4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsImmunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: MAP3K4 antibody detects endogenous levels of MAP3K4. Description: The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors. This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at the C terminus. The N-terminal nonkinase domain may contain a regulatory domain. Expre
ImmunogenImmunogen: A synthesized peptide derived from human MAP3K4 Subcellular Location: Cytoplasm > Perinuclear Region. Localized in perinuclear vesicular-like structures, probably golgi-associated vesicles. Tissue Specificity: Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (92%), Bovine (100%), Horse (100%), Rabbit (100
Other Names[dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); FLJ42439; KIAA0213; M3K4_HUMAN; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP3K4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; MEKK 4; MEKK4; Mitogen-activated protein kinase kinase kinase 4; MTK1; predicted protein of HQ0412; PRO0412; RP3-473J16.4; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of]
Gene, Accession #[MAP3K4], Gene ID: 4216, NCBI: NP_001278887.1, UniProt: Q9Y6R4
Catalog #MBS9600572
Price$240, $280
Order / More InfoMAP3K4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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