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Antigenic Specificity | MAP3K4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAP3K4 antibody detects endogenous levels of MAP3K4. Description: The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors. This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at the C terminus. The N-terminal nonkinase domain may contain a regulatory domain. Expre |
Immunogen | Immunogen: A synthesized peptide derived from human MAP3K4 Subcellular Location: Cytoplasm > Perinuclear Region. Localized in perinuclear vesicular-like structures, probably golgi-associated vesicles. Tissue Specificity: Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (92%), Bovine (100%), Horse (100%), Rabbit (100 |
Other Names | [dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); FLJ42439; KIAA0213; M3K4_HUMAN; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP3K4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; MEKK 4; MEKK4; Mitogen-activated protein kinase kinase kinase 4; MTK1; predicted protein of HQ0412; PRO0412; RP3-473J16.4; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of] |
Gene, Accession # | [MAP3K4], Gene ID: 4216, NCBI: NP_001278887.1, UniProt: Q9Y6R4 |
Catalog # | MBS9600572 |
Price | $240, $280 |
Order / More Info | MAP3K4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |