SHANK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySHANK1
Clone[S22-21]
Host SpeciesMouse
Reactive Speciesmouse, human, rat
IsotypeIgG1
FormatATTO 680 conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionBackground Info: Detects ~190-220 kDa (alternative splice variants). No cross-reactivity against Shank2 or Shank3. Scientific Background: Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (3). Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo (4).
Immunogenn/a
Other Names[Spank1; Sstrip; GKAP/SAPAP interacting protein; OTTHUMP00000174437; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHAN1_HUMAN; SHANK 1; Shank1; Shank1a], [Shank1; Shank1; Spank1; Sstrip; Shank1a; Shank1; SSTR-interacting protein; SSTRIP]
Gene, Accession #Gene ID: 78957, NCBI: NP_113939.2, UniProt: Q9WV48
Catalog #MBS800153
Price$440
Order / More InfoSHANK1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Sheng M., and Kim E. (2000) Journal of Cell Science. 113: 1851-1856. 4. Hung A.Y., et al. (2008) J Neurosci. 28(7): 1697-1708.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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