GPR126 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GPR126 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: GPR126 antibody detects endogenous levels of total GPR126. Function: G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (By similarity). Couples to G(i)-proteins as well as G(s)-proteins (PubMed:24227709). Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709). Regulates neural, cardiac and ear development via G-protein-and/or N-terminus-dependent signaling (By similarity). May act as a receptor for PRNP which may promote myelin homeostasis (By similarity).Subunit Structure: Interacts with Laminin-2; this interaction stabilizes the receptor in an inactive state. Laminin-2 polymerization could faci |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Detected on the cell surface of activated but not resting umbilical vein. Tissue Specificity: Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells. Predicted Cross Reactivity: Bovine, Horse, Sheep, Dog Similarity: Bovine (91%), Horse (91%), Sheep (91%), Dog (91%) |
| Other Names | [adhesion G protein coupled receptor G6; APG1; Developmentally regulated G protein coupled receptor; Developmentally regulated G-protein-coupled receptor; dj287g14.2; DREG; G protein coupled receptor 126; G-protein coupled receptor 126; GP126_HUMAN; GPR126; HBV PreS1 transactivated protein 2; HBV PreS1-transactivated protein 2; LCCS9; OTTHUMP00000017320; OTTHUMP00000237093; OTTHUMP00000237094; OTTHUMP00000237115; PR126; Probable G protein coupled receptor 126 [Precursor]; Probable G protein coupled receptor 126; Probable G-protein coupled receptor 126 [Precursor]; Probable G-protein coupled receptor 126; PS1TP2; Vascular inducible G protein coupled receptor; Vascular inducible G protein-coupled receptor; VIGR] |
| Gene, Accession # | [GPR126], Gene ID: 57211, NCBI: NP_001027566.1, UniProt: Q86SQ4 |
| Catalog # | MBS9606397 |
| Price | $240, $280 |
| Order / More Info | GPR126 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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