PABPN1 (C-term), 270-298 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPABPN1 (C-term), 270-298
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis PABPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-298 amino acids from the C-terminal region of human PABPN1. This gene encodes an abundant nuclear protein that bindswith high affinity to nascent poly(A) tails. The protein isrequired for progressive and efficient polymerization of poly(A)tails on the 3' ends of eukaryotic genes and controls the size ofthe poly(A) tail to about 250 nt. At steady-state, this protein islocalized in the nucleus whereas a different poly(A) bindingprotein is localized in the cytoplasm. An expansion of thetrinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end ofthe coding region of this gene leads to autosomal domina
Immunogenn/a
Other Names[Polyadenylate-binding protein 2; PABP-2; Poly(A)-binding protein 2; Nuclear poly(A)-binding protein 1; Poly(A)-binding protein II; PABII; Polyadenylate-binding nuclear protein 1; PABPN1; PAB2; PABP2]
Gene, Accession #[PABPN1], Gene ID: 8106, NCBI: NP_004634.1, UniProt: Q86U42
Catalog #MBS9211915
Price$165, $370
Order / More InfoPABPN1 (C-term), 270-298 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Hurt, J.A., et al. J. Cell Biol. 185(2):265-277(2009) Kuo, H.C., et al. J. Neurol. Sci. 278 (1-2), 21-24 (2009) : Tavanez, J.P., et al. PLoS ONE 4 (7), E6418 (2009) : Maksimova, N.R., et al. Zh Nevrol Psikhiatr Im S S Korsakova 108(6):52-60(2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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