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Antigenic Specificity | PABPN1 (C-term), 270-298 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PABPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-298 amino acids from the C-terminal region of human PABPN1. This gene encodes an abundant nuclear protein that bindswith high affinity to nascent poly(A) tails. The protein isrequired for progressive and efficient polymerization of poly(A)tails on the 3' ends of eukaryotic genes and controls the size ofthe poly(A) tail to about 250 nt. At steady-state, this protein islocalized in the nucleus whereas a different poly(A) bindingprotein is localized in the cytoplasm. An expansion of thetrinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end ofthe coding region of this gene leads to autosomal domina |
Immunogen | n/a |
Other Names | [Polyadenylate-binding protein 2; PABP-2; Poly(A)-binding protein 2; Nuclear poly(A)-binding protein 1; Poly(A)-binding protein II; PABII; Polyadenylate-binding nuclear protein 1; PABPN1; PAB2; PABP2] |
Gene, Accession # | [PABPN1], Gene ID: 8106, NCBI: NP_004634.1, UniProt: Q86U42 |
Catalog # | MBS9211915 |
Price | $165, $370 |
Order / More Info | PABPN1 (C-term), 270-298 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Hurt, J.A., et al. J. Cell Biol. 185(2):265-277(2009) Kuo, H.C., et al. J. Neurol. Sci. 278 (1-2), 21-24 (2009) : Tavanez, J.P., et al. PLoS ONE 4 (7), E6418 (2009) : Maksimova, N.R., et al. Zh Nevrol Psikhiatr Im S S Korsakova 108(6):52-60(2008) |