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Antigenic Specificity | NR2B, phosphorylated |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of human NR2B when phosphorylated at tyrosine 1474. Species Crossreactivity: mouse and rat. NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B or NR2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA). Properties of NMDAR include mo |
Immunogen | Immunogen: Synthetic phosphopeptide corresponding to human NMDAR2B around the phosphorylation site of Tyr1474 (H-V-YP-E-K). |
Other Names | NR2B, phosphorylated (Tyr1474) (NMDA R2b, NMDAR2B, N-methyl-D-aspartate Receptor Subunit 3, GRIN2B, Glutamate [NMDA] Receptor Subunit epsilon-2, NR2B, N-methyl-D-aspartate Receptor Subunit 2B, NR3) |
Gene, Accession # | NCBI: CAP08277.1, UniProt: B5QTB1 |
Catalog # | MBS626809 |
Price | $445 |
Order / More Info | NR2B, phosphorylated Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |