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Antigenic Specificity | RSK2 |
Clone | [5H5-C11-F10] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). UniPort Summary Function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B |
Immunogen | Immunogen: Purified recombinant fragment of human RSK2 expressed in E Coli. Sequence Similarities: Contains 2 protein kinase domains. |
Other Names | [RPS6KA3; CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3], [RPS6KA3; RPS6KA3; CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3] |
Gene, Accession # | [RSK2], Gene ID: 6197, NCBI: NP_004577.1, UniProt: P51812 |
Catalog # | MBS476230 |
Price | $335 |
Order / More Info | RSK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |