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Antigenic Specificity | Caspase-6 |
Clone | [MCH2 14 1-190] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase-6 (Cysteine-Requiring Aspartate Proteases) is part of a family of intracellular cysteine proteases that cleave their substrates after aspartic acid residues. These proteases play an integral role in inducing apoptosis in cells. Procaspase-6 (Mch2), a member of the ICE/ced-3 subfamily, is an inactive proenzyme that is activated to form caspase-6 by proteolytic cleavage at certain aspartic acid residues. During cleavage, the N-terminal is removed and the proenzyme is converted into a large (p18) and small (p11) subunits. |
Immunogen | Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-6 protein and mouse myeloma cells. |
Other Names | [Cysteine-requiring Aspartate Protease-6; Apoptotic protease Mch-2], [CASP6; CASP6; MCH2; MCH2; CASP-6] |
Gene, Accession # | Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
Catalog # | MBS395327 |
Price | $340 |
Order / More Info | Caspase-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |