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Antigenic Specificity | KDM1A/LSD1 |
Clone | [2E7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human AOF2. Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9'(H3K9me) of histone H3, thereby acting as a coactivator or acorepressor, depending on the context. Acts by oxidizing the substrateby FAD to generate the corresponding imine that is subsequentlyhydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, aspecific tag for epigenetic transcriptional activation. Demethylatesboth mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. |
Immunogen | Immunogen: AOF2 (NP 055828, 753 a.a. ~ 852 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Rabbit to Human KDM1A/LSD1; KDM1A; BHC110; KDM1; LSD1; AOF2; KIAA0601] |
Gene, Accession # | [KDM1A/LSD1], Gene ID: 23028, NCBI: NP_055828.2, UniProt: O60341 |
Catalog # | MBS2400647 |
Price | $605 |
Order / More Info | KDM1A/LSD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |