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Antigenic Specificity | Human Histone H2A.Z |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
Immunogen | Immunogen: Recombinant human Histone H2A.Z protein (1-128aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-67218 |
Other Names | [H2A/z; H2AFZ; H2AZ], [H2AFZ; H2AFZ; H2AZ; H2A.z; H2A/z; H2A.Z-1; H2AZ; H2A/z] |
Gene, Accession # | [H2AFZ], Gene ID: 3015, NCBI: NP_002097.1, UniProt: P0C0S5 |
Catalog # | MBS1491677 |
Price | $120, $160 |
Order / More Info | Human Histone H2A.Z Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |