TFE3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTFE3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total TFE3 protein. Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
Other Names[BHLHE33; TFEA; RCCP2]
Gene, Accession #[TFE3], Gene ID: 7030, NCBI: NP_001269071.1, UniProt: P19532
Catalog #MBS9402688
Price$200, $255
Order / More InfoTFE3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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