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Antigenic Specificity | NBN |
Clone | [7E4C2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Immunogen | Immunogen: Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. Coli. |
Other Names | [ATV; NBS; P95; NBS1; AT-V1; AT-V2] |
Gene, Accession # | [NBN], Gene ID: 4683, NCBI: NP_002476.2, UniProt: O60934 |
Catalog # | MBS8539124 |
Price | $280 |
Order / More Info | NBN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |