Human CD11a Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD11a |
| Clone | [38] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD11a (a L integrin) complexes with CD18 (b2 integrin) to form the LFA-1 heterodimer adhesion molecule which binds to three ICAM's 1, 2, and 3, also designated CD54, CD102, and CD50 respectively. LFA-1 is expressed on lymphocytes, monocytes and neutrophils and plays a role in cell-cell adhesion. Antibody 38 recognizes the I domain of the integrin alpha L subunit (CD11a) of about 180 kd. Antibody 38 blocks binding of ICAM-1 and ICAM-3 to LFA-1 at 5-10 mg/ml. |
| Immunogen | Immunogen: Human monocytes |
| Other Names | n/a |
| Gene, Accession # | [CD11a] |
| Catalog # | MBS666223 |
| Price | $310 |
| Order / More Info | Human CD11a Antibody from MYBIOSOURCE INC. |
| Product Specific References | I. Dransfield & N. Hogg, (1989) EMBO J 12: 3759-3765. Leukocyte Typing V (S.F. Schlossman,et al, eds.) Oxford University Press, Oxford, (1995) p. 1581-1592. R.C. Landis, et al, (1994) J Cell Biol 126: 529-537. C.L. Holness, et al, (1995) J Biol Chem 270: 877-884. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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