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Antigenic Specificity | Human M-CSF R |
Clone | [5V36] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | M-CSF receptor, the product of the c- fms protooncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulinlike domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. M-CSF receptor is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. Human M-CSF receptor cDNA encodes a 972 amino acid (aa) type I membrane protein with a 19 aa signal peptide, a 493 aa extracellular region containing the ligandbinding domain, a 25 aa transmembrane domain, and a 435 aa cytoplasmic domain. The human MCSF R ECD shares 60%, 64%, 72%, |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of M-CSF R extracellular domain. |
Other Names | [CSF1; MCSF; CSF-1], [CSF1R; CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R; FMS; CSF-1-R; CSF-1R; M-CSF-R] |
Gene, Accession # | [M-CSF R], Gene ID: 1436, NCBI: NP_005202.2, UniProt: P07333 |
Catalog # | MBS690397 |
Price | $490 |
Order / More Info | Human M-CSF R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |