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Antigenic Specificity | Human CD126 (IL-6R) |
Clone | [B-R6] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD126 antibody, clone B-R6 recognizes human Interleukin-6 receptor subunit alpha, also known as CD126, IL-6R or Membrane glycoprotein 80. Human CD126 is a 468 amino acid single pass type I transmembrane glycoprotein bearing a single Ig-like C2 type domain, two fibronectin type III domains and a single WSXWS motif which may be involved in receptor avtivation (Daqil et al. 2012). Mouse anti Human CD126 antibody, clone B-R6 inhibits IL-6 mediated proliferation of XG-1 cells (Lu et al. 1995) and partially blocks binding of IL-6 to its receptor (Fourcin et al. 1994), clone B-R6 recognizes both the soluble and membranous human CD126 Removal of Sodium azide is recommended prior to use in functional assays. MyBioSource recommend th |
Immunogen | n/a |
Other Names | [interleukin-6 receptor subunit alpha isoform 1; Interleukin-6 receptor subunit alpha; interleukin-6 receptor subunit alpha; CD126 antigen; IL-6 receptor subunit alpha; IL-6R 1; membrane glycoprotein 80; interleukin 6 receptor; IL-6R 1; Membrane glycoprotein 80; gp80; CD_antigen: CD126], [IL6R; IL6R; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; gp80] |
Gene, Accession # | [CD126], Gene ID: 3570, NCBI: NP_000556.1, UniProt: P08887 |
Catalog # | MBS213171 |
Price | $300 |
Order / More Info | Human CD126 (IL-6R) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |