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Antigenic Specificity | Human DENN / MADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to amino acids near the carboxy terminus of human MADD. MAP kinase-activating death domain protein (MADD) was initially identified as the type 1 tumor necrosis factor receptor (TNFR1) associated protein though their death domains. Overexpression of MADD activates MAP kinases ERK and JNK and induces the phosphorylation of cytosolic phospholipase A2 (1). MADD shares 98% identity with DENN (for differentially expressed in neoplastic vs. normal cells), which was recently identified as a substrate for c-jun N-terminal kinase 3 (JNK3). |
Immunogen | Immunogen Description: Synthetic peptide from human MADD. |
Other Names | [DENN / MADD (C-Terminus) IHC-plus; MADD; DENN; IG20; KIAA0358; Rab3 GDP/GTP exchange factor; RAB3GEP; Human DENN; MADD], [MADD] |
Gene, Accession # | [DENN], Gene ID: 8567, NCBI: NP_003673.3, UniProt: Q8WXG6 |
Catalog # | MBS240336 |
Price | $530 |
Order / More Info | Human DENN / MADD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |