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Antigenic Specificity | PDPK1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse PDPK1 |
Other Names | [3-phosphoinositide-dependent protein kinase 1 isoform A; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide dependent protein kinase 1] |
Gene, Accession # | [PDPK1], Gene ID: 18607, NCBI: NP_035192.2, UniProt: Q9Z2A0 |
Catalog # | MBS3223693 |
Price | $335 |
Order / More Info | PDPK1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |