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Antigenic Specificity | JUP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). |
Immunogen | Immunogen: Recombinant human Junction plakoglobin protrin Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30997 / sc-30996 / sc-30998 / sc-7900 / sc-1497-R |
Other Names | [Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3; CTNNG; DP3; JUP], [JUP; JUP; DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12; CTNNG; DP3] |
Gene, Accession # | [JUP], Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923 |
Catalog # | MBS1494711 |
Price | $160, $235 |
Order / More Info | JUP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |