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Antigenic Specificity | LBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Lipopolysaccharide-binding protein(LBP) detection. Background: Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of L |
Immunogen | Immunogen: E Coli-derived human LBP recombinant protein (Position: L177-E446). Human LBP shares 68.5% and 69.6% amino acid (aa) sequence identity with mouse and rat LBP, respectively. |
Other Names | [Bpifd2; LBP; LBP1; Ly88; P18428; Lipopolysaccharide-binding protein], [LBP; LBP; BPIFD2; LBP] |
Gene, Accession # | [LBP], Gene ID: 3929, NCBI: NP_004130.2, UniProt: P18428 |
Catalog # | MBS178622 |
Price | $280 |
Order / More Info | LBP Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: LBP lipopolysaccharide binding protein.2. Gray PW, Corcorran AE, Eddy RL Jr, Byers MG, Shows TB (March 1993). The genes for the lipopolysaccharide binding protein (LBP) and the bactericidal permeability increasing protein (BPI) are encoded in the same region of human chromosome 20. Genomics. 15 (1): 188-90. |