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Antigenic Specificity | Human Suppressor of cytokine signaling 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Immunogen | Immunogen: Recombinant human Suppressor of cytokine signaling 2 protein (1-198aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7007 / sc-7008 / sc-9022 |
Other Names | [SOCS-2; Cytokine-inducible SH2 protein 2; CIS-2; STAT-induced STAT inhibitor 2; SSI-2; SOCS2; CIS2; SSI2; STATI2], [SOCS2; SOCS2; CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2; CIS2; SSI2; STATI2; SOCS-2; CIS-2; SSI-2] |
Gene, Accession # | [SOCS2], Gene ID: 8835, NCBI: NP_001257396.1, UniProt: O14508 |
Catalog # | MBS1494940 |
Price | $120, $160 |
Order / More Info | Human Suppressor of cytokine signaling 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |